Nanoparticles: a boon to drug delivery, therapeutics, diagnostics and imaging

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This review article focuses on the potential of nanotechnology in medicine and discusses different nanoparticulate drug-delivery systems including polymeric NPs, ceramic NPs, magnetic NPs, polymeric micelles and dendrimers as well as their applications in therapeutics, diagnostics and imaging.

Drug delivery is an interdisciplinary and independent field of research and is gaining the attention of pharmaceutical researchers, medical doctors and industry. A safe and targeted drug delivery could improve the performance of some classic medicines already on the market, and moreover, will have implications for the development and success of new therapeutic strategies such as anticancer drug delivery, peptide and protein delivery and gene therapy.

In the last decade, several drug-delivery technologies have emerged and a fascinating part of this field is the development of nanoscale drug delivery devices.

Nanoparticles (NPs) have been developed as an important strategy to deliver conventional drugs, recombinant proteins, vaccines and more recently, nucleotides. NPs and other colloidal drug-delivery systems modify the kinetics, body distribution and drug release of an associated drug.

This comprehensive review focuses on different nanoparticulate drug-delivery systems including polymeric NPs, ceramic NPs, magnetic NPs, polymeric micelles and dendrimers as well as their applications in therapeutics, diagnostics and imaging.

Source: sciencedirect

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3 Comments

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  1. TGI

    @Alan, Comments are well taken. Yes certainly there is a need to continuously address the toxicity factor as well. Following is the recent article to that end.

    nanomaterial toxicity: the health consequences of human exposure to nanomaterials.
    https://tginnovations.wordpress.com/2012/09/20/nanomaterial-toxicity-the-health-consequences-of-human-exposure-to-nanomaterials/

    It may not be inappropriate to mention here that I am interested and planning for a short survey on:

    “The impact of traffic pollution (nanoparticles in workplace and marketplace) especially on traffic police in selected areas who may be spending extended ours at traffic signals.

    I will begin this study once I am encouraged with the necessary support to successfully complete the study.

    Like

  2. Alan Schmukler

    I’m glad there’s a medically useful place for Nano. However, the down side is that Nano particles are finding their way into many consumer products and even foods and sun tan lotions. The problem is that they migrate to the vital organs. What ever happened to the precautionary principle?.

    Like

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