E. faecalis contributes to root canal infections, urinary tract infections, endocarditis, meningitis, bacteremia, and other infections

· TGI - Health, TGI - Pathogens
Authors

“The cytolysin protein made by Enterococcus faecalis consists of two compounds that have no activity by themselves but when combined kill human cells,” van der Donk says. “We know from epidemiological studies that if you are infected with a strain of E. faecalis that has the genes to make cytolysin, you have a significantly higher chance of dying from your infection.” says University of Illinois chemistry and Institute for Genomic Biology professor Wilfred van der Donk, who conducted the study with graduate student Weixin Tang.

E. faecalis contributes to root canal infections, urinary tract infections, endocarditis, meningitis, bacteremia, and other infections.

Authors hope that the new findings, reported in Nature Chemical Biology, should help scientists find new ways to target the enterococcal cytolysin protein, a “virulence factor that is associated with acute infection in humans.”

Read more of this

1 Comment

Comments RSS
  1. Array linked to this post.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: