Meclizine, an over-the-counter drug used for decades to treat nausea and motion sickness, has the potential for new uses to treat certain infectious diseases and some forms of cancer, according to Vishal M. Gohil, Texas A&M AgriLife Research biochemist.
The research on meclizine appears in the current online version of the Journal of Biological Chemistry.
“We found a particular enzyme which is inhibited by meclizine has been proposed (in other research) to be a drug target
for the treatment of many diseases
, including infectious diseases like malaria and African sleeping sickness
,” Gohil said. “And this pathway has also been proposed to be a critical pathway for the proliferation of cancer cells.”